Eine der Repliken auf http://heart.bmj.com/content/early/2013/07/30/heartjnl-2013-304262.abstract/reply , von Andrea Messori et al., sagt:
On the basis of this TSA [trial-sequential analysis], the use of beta-blockade in non-cardiac surgery is statistically proven to be ineffective (futility) and, additionally, is very likely to be harmful.
Mir persönlich reicht das, um Don Poldermans Rechtfertigung zumindest stark anzuzweifeln.